Can it Happen?

3D Molecular Imaging In Solution:

from small proteins to delivery particles

Monday, December 2, 2024

from 12:00 PM EST

In-person at:

The Japan Society of Boston presents a free networking talk and lunch at The Foundry in Cambridge. 

Our speaker, Dr. Takashi Sato, is Chief Scientist & Technical Architect in the Life Science Product Division at Rigaku Corporation. He will give a talk about disruptive new technologies for 3D imaging and characterization of biomacromolecules and pharmaceutics in solution, named Electron Density Topography (EDT).

It enables scientists to visualize a newly designed molecule and engaged complex overnights or confirm the mode of complex formation as well as epitopes/paratopes based on 3D images in solution. This technology enables not only 3D images of the molecule but also molecular flexibilities, dynamic characteristics, and even the internal ratio of components of a molecular complex, like N/P for AAV vectors.

The instrument is a kind of solution molecular microscope that provides 3D characteristics in daily study or development work for all researchers.

Check out the following article for useful background information on this topic: 

"For protein imaging, the answer is in solution"

The half hour talk will be followed by a Q&A session and an opportunity to network with other Japanese science/technology industry professionals. Light lunch will be served.

This event is sponsored by the generous support from Japan Airlines.

For any questions, please email info@japansocietyboston.org

About the Speaker: 

Dr. Takashi Sato, PhD is a Chief Scientist and Technical Architect of the Life Science Product Division of Rigaku Corporation, a long-established company in X-ray analytical instruments, primarily well-known in laboratory protein crystallography and devices for synchrotron beamlines. He is currently leading the R&D of EDT and MAXS technologies for 3D analysis of therapeutic biomolecules to connect the unmet needs of state-of-the-art technology to the fields where it is entirely unfamiliar with the tech. His works are firmly based on the users' point of view with his decades of experience as a university professor and company researcher in protein science, biophysics, organic chemistry, basic biology, and medicinal sciences, especially pathology, physiology, and obstetrics/gynecology.